What are the hardest college classes in America?

I've heard rumors about some notoriously difficult college courses and I'm a little curious (and somewhat terrified) to know. Can anyone shed some light on what the toughest college classes offered in the USA could be? Just to prep my brain for what lies ahead.

In terms of difficulty, the consensus is that it can largely depend on the teaching style of the professor, your interest and proficiency in the subject matter, and the university you're attending. However, certain disciplines inherently require more extensive study, critical thinking, and comprehension skills.

1. Organic Chemistry: Students often cite organic chemistry as one of the hardest college classes. It involves understanding the structure, properties, composition, reactions, and preparation of carbon-containing compounds, which includes not only hydrocarbons but also compounds with any number of other elements. The sheer volume of information to remember makes this class challenging.

2. Quantum Mechanics: Usually a course for Physics majors, quantum mechanics involves a high level of math and abstract conceptual thinking, making it a difficult subject for many.

3. Advanced Calculus: This class requires a strong foundation in basic calculus concepts and involves complex theories that often require a high level of abstract thinking.

4. Anatomy and Physiology: These classes, often found in pre-med or nursing tracks, are considered difficult due to the large amount of memorization required.

5. Econometrics: This is often referred to as a difficult class because it applies statistical mathematics to economic data. It involves complex mathematical theories and the use of statistical software.

6. Law School Classes: Constitutional Law, or any Law class really, is often considered tough. Memorization of legal terms and understanding of complex legal principles can make these classes challenging.

Remember, what one person might find extremely challenging, another might find engaging and doable. Difficulty in academic subjects often varies greatly on individual strengths and interests. It’s also important to note that professors can often add to the difficulty depending on their teaching style, course requirements, and expectations. Solid study habits, good time management, and utilizing available resources such as study groups, tutors, and office hours can greatly help in making these "difficult" classes more manageable.